"Widely considered among healthcare professionals to be the "master" antioxidant, Glutathione plays a critical role in preventing damage to cells throughout the body. It protects against free radicals and heavy metals while supporting healthy immune functions.
We created No. 6 S-Acetyl Glutathione to be well-absorbed and more stable throughout the digestive tract than other forms on the market. Our stomach acid-resistant capsules further protect their stability upon ingestion, allowing the nutrients to be fully dispersed throughout the body."
• Intracellular Antioxidants • Healthy Cell Function and Healthy Aging • Detoxification • Healthy Immune Response • Enhances Antioxidant Activity of Vitamins C and E
DIRECTIONS 1 capsule in the morning 1 capsule in the evening
Reduced glutathione, commonly known as glutathione or GSH, is a tripeptide consisting of L-glutamine, L-cysteine, and glycine. It is ubiquitous in living systems. Glutathione biosynthesis can be affected by biochemical individuality and/or dietaryfactors. Chronic oxidative stress can also deplete cellular glutathione. Precursors to glutathione, such as whey protein, vitamin C, and glutamine, are often recommended to boost glutathione levels in the body; however, results are inconsistent.
Biological individuality is such that not every body has equivalent ability to metabolize the precursor to raise glutathione.* Why Not Give Pure Glutathione? Unfortunately, most oral forms of glutathione are foul smelling, but more importantly,the majority of an oral dose is oxidized before it can be absorbed and used by the cells. This formulation delivers a unique preparation of glutathione that overcomes these usual limitations. The stability of S-acetylglutathione through the intestinal wall and the plasma is well documented in the literature. Oral intake of S-acetylglutathione increases total glutathione and percent-reduced glutathione. Percent-reduced glutathione is a very significant biomarker of health status.
Mechanism of Absorption S-acetylglutathione, a lipid-like compound, is taken up intact by chylomicrons in the gut. The acetyl bond is placed on its thiol group or sulfur group, which prevents oxidation and allows the molecule to pass diffusively into the cell after absorption in the gut. The bond is then cleaved by non-specific enzymes inside the cell. Acetylation prevents the breakdown of glutathione, and S-acetylglutathione does not require energy expenditure to be cleaved to reduced glutathione once it crosses the cell wall.*[1-8]
Antioxidant Activity Glutathione functions extensively in tissues and organs throughout the body. It plays critical roles in protecting the body from oxidative stress, maintaining cellular functions, and supporting healthy immune function.[1,4] Many factors can increase cellular exposure to oxidative insult, and therefore increase cellular consumption of nutrients—such as glutathione—that provide antioxidant activity. This may result in a fierce cycle of oxidative stress and challenges to detoxification. Complete biotransformation and protection from oxidative stress are important to maintaining cellular integrity and tissue health.
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